Fortuna Sittard 2 x 2 Go Ahead EaglesShawn Adewoye 29' (gol contra), Philip Brittijn 45', Luka Tunjic 85', Gerrit Nauber 90'
NEC Nijmegen 5 x 0 ExcelsiorDirk Proper 14', Koki Ogawa 52', Koki Ogawa 59', Bryan Linssen 67', Tjaronn Chery 82' (pênalti)
Feyenoord 2 x 0 NAC BredaSem Steijn 3', Ayase Ueda 55'
SC Heerenveen 1 x 1 FC VolendamLuuk Brouwers 4', Ozan Kökcü 65'
PSV 6 x 1 Sparta RotterdamRuben van Bommel 3', Ivan Perišić 40', Sergiño Dest 45', Joey Veerman 50', Sayfallah Ltaief 63', Guus Til 70', Yarek Gasiorowski 77'
PEC Zwolle 1 x 0 FC TwenteThijs Oosting 8'
Ajax 2 x 0 TelstarWout Weghorst 19', Wout Weghorst 83'
AZ 4 x 1 FC GroningenDenso Kasius 5', Troy Parrott 18' (pênalti), Stije Resink 32' (gol contra), Marco Rente 44', Troy Parrott 87'
FC Utrecht 4 x 0 Heracles AlmeloGjivai Zechiël 33', David Min 62', Victor Jensen 70', Dani de Wit 79'
