TP Mazembe 4 x 0 Al Hilal OmdurmanJean Louis Barthélémy Diouf 22', Ibrahima Keita 29', Merceil Ngimbi Vumbi 58', Suleman Shaibu 89' (pênalti)
Al Ahly 1 x 2 Orlando PiratesRelebohile Mofokeng 53', Hussein El Shahat 69', Tshegofatso Mabasa 83'
CR Belouizdad 6 x 0 Stade d'AbidjanAbderrahmane Meziane 17', Mohamed Islam Belkhir 27', Mohamed Islam Belkhir 37', Aimen Mahious 49', Rezki Hamroune 87', Merouane Zerrouki 90'
ES Tunis 4 x 1 Sagrada EsperançaAchref Jabri 17', Yan Sasse 23', Dabanda 45', Achref Jabri 55', Achref Jabri 59'
Pyramids FC 6 x 0 DjolibaSodiq Awujoola 2', Marwan Hamdi 10', Mostafa Fathi 53', Ramadan Sobhi 60' (pênalti), Abdelrahman Magdi 66', Youssef Obama 77'
Mamelodi Sundowns 1 x 1 FAR RabatPeter Shalulile 12', Amine Zouhzouh 83'
Raja Casablanca 1 x 0 Maniema UnionAdam Ennaffati 45' (pênalti)
