Al Khalidiyah 1 x 2 Al-Ahli DohaDriss Fettouhi 65', Mohamed Al Romaihi 74', Sekou Oumar Yansane 90'
Al Wihdat 2 x 1 MuharraqJuninho Piauiense 33', Mostafa Moawad 45', Amer Jamous 58'
Sepahan 2 x 0 Al HusseinArya Yousefi 73', Mohammad Asgari 90'
True Bangkok United 1 x 1 SelangorRungrath Poomchantuek 51', Chrigor Moraes 90'
Lion City Sailors FC 3 x 2 PersibLennart Thy 9', Frans Dhia Putros 11', Andrew Jung 56', Shawal Anuar 62', Anderson Lopes 71'
Andijan 1 x 1 ArkadagIsmahil Akinade 63', Didar Durdyýew 68'
Istiqlol Dushanbe 0 x 4 Al NassrJoão Félix 12' (pênalti), Mohamed Simakan 40', Sadio Mané 84', Ayman Yahya 90'
Al Zawra'a 2 x 1 GoaKadhim Raad 38', Dhurgham Ismail 51' (gol contra), Hasan Abdulkareem 65'
Esteghlal 1 x 1 Al WaslSaeed Saharkhizan 6', Hugo 63'
Macarthur 2 x 1 Wofoo Tai PoIgor Sartori 24', Luke Vickery 50', Luke Vickery 70'
Ratchaburi Mitrphol FC 2 x 0 Thép Xanh Nam ĐịnhSidcley 90', Ikhsan Fandi 90'
Eastern 0 x 5 Gamba OsakaRyoya Yamashita 4', Shota Fukuoka 19', Shuto Abe 33', Deniz Hümmet 59', Gaku Nawata 75'
Pohang Steelers 2 x 0 BG Pathum UnitedHo-jae Lee 43', Ho-jae Lee 54'
Công an Hà Nội 2 x 1 Beijing GuoanLin Liangming 11', Stefan Mauk 76', Dinh Bac Nguyen 90'
Tampines Rovers 5 x 3 KayaHide Higashikawa 7', Takeshi Yoshimoto 37', Trent Buhagiar 47', Hide Higashikawa 56', Mike Ott 66', Paolo Bugas 74', Amirul Adli Azmi 85' (gol contra), Faris Ramli 86'
