Al Wihdat 1 x 0 Istiqlol DushanbeOusseynou Gueye 77'
Sepahan 3 x 1 Al SharjahMohammad Amin Hazbavi 12', Arya Yousefi 45', Luan Pereira 61', Javad Aghaeipour 90'
Thép Xanh Nam Định 3 x 2 Tampines RoversAmirul Adli Azmi 38', Seia Kunori 48', Caio César 57', Joseph Mpande 80', Lucas 90'
True Bangkok United 4 x 1 Lee Man FCEverton Camargo 41', Richairo Zivkovic 67', Wanchai Jarunongkran 73', Muhsen Al-Ghassani 78', Richairo Zivkovic 90'
Altyn Asyr 0 x 4 Al TaawounMusa Barrow 36', Sultan Mandash 40', Musa Barrow 67', Ahmed Saleh Bahusayn 88'
Nasaf 1 x 2 Al HusseinSharof Mukhiddinov 23', Reziq Bani Hani 31', Reziq Bani Hani 45'
Tractor Sazi 7 x 0 RavshanKholmurod Nazarov 4' (gol contra), Sokol Cikalleshi 14', Sokol Cikalleshi 25' (pênalti), Sokol Cikalleshi 27', Amirhossein Hosseinzadeh 45', Ricardo Alves 49' (pênalti), Amirhossein Hosseinzadeh 69'
Al Khalidiyah 4 x 1 Al Quwa Al JawiyaKomail Al-Aswad 4', Dhurgham Ismail 52', Komail Al-Aswad 56', Alaa Abbas 79', Komail Al-Aswad 90'
Al Kuwait 3 x 3 Shabab Al Ahli DubaiFederico Cartabia 34', Arsène Zola 38', Mohamed Jasim Marhoon 42', Guilherme Bala 68', Amoory 71', Luka Milivojevic 90'
Sydney 0 x 1 Sanfrecce HiroshimaMutsuki Kato 60'
Dynamic Herb Cebu 2 x 9 SCG Muangthong UnitedFelicio Brown Forbes 7', Poramet Arjvirai 13', Gutho Mijland 20', Gutho Mijland 23', Kakana Khamyok 37', Kakana Khamyok 39', Felicio Brown Forbes 45', Poramet Arjvirai 45', Poramet Arjvirai 51', Purachet Thodsanit 65', Songwut Kraikruan 82'
Jeonbuk Motors 1 x 0 SelangorTiago Orobó 22'
Eastern 1 x 2 KayaDaizo Horikoshi 32', Marcos Gondra Krug 70', Robert Lopez 86'
Lion City Sailors FC 2 x 3 PersibShawal Anuar 9', Maxime Lestienne 23', David Aparecido da Silva 82', Mateo Kocijan 90', Tyronne Gustavo del Pino Ramos 90'
Zhejiang 1 x 2 Port FCFranko Andrijašević 7', Lonsana Doumbouya 54', Felipe Amorim 90'
